Medical Director – Safety & Risk Management (SERM)

About the role

The SERM Medical Director provides medical and scientific leadership for the safety evaluation and risk management of GSK’s oncology assets in clinical development. This senior position is responsible for interpreting safety data, identifying signals, and delivering evidence‑based recommendations to support benefit‑risk decisions.

Key responsibilities

• Lead pharmacovigilance and risk‑management activities for assigned oncology assets and clinical trials.
• Define and drive safety‑evaluation strategy across the clinical development lifecycle.
• Analyse clinical data, literature and emerging evidence to identify and assess safety signals.
• Provide expert medical input for global regulatory submissions.
• Escalate safety concerns in line with governance processes and represent Safety on cross‑functional Clinical Matrix and Project Teams.
• Lead or contribute to Safety Review Teams and mentor colleagues.
• Present safety issues to senior governance committees and interact with regulatory authorities and external experts.

Required profile

• Medical degree with extensive experience in pharmacovigilance and risk management, preferably in oncology.
• Proven ability to interpret complex safety data and make benefit‑risk decisions.
• Strong leadership and matrix‑management skills across global, cross‑functional teams.
• Excellent communication skills for influencing senior stakeholders and regulatory bodies.

Required skills

• Pharmacovigilance
• Risk Management
• Clinical Data Analysis
• Regulatory Submissions
• Oncology therapeutic area knowledge